Erythema Toxicum

  1. Benign rash in up to 70% of nbn.
  2. Small yellow-white papules/vesicles on erythematous base
  3. On any part of body, commonly face/trunk/extremities.
  4. Can disappear/reappear moments/hours later on a different part of body.
  5. May last from a few hours to several days. Not really seen when newly born. Peak incidence during DOL2, but can occur up to 3 mos of age
  6. In a smear of a papule, will see eosinophils.

Erythema toxicum is a benign, self-limited eruption that occurs in approximately 50% of term newborns. It is characterized by erythematous macules 2 to 3 cm in diameter that have a central papule, vesicle, or pustule. The eruption typically begins at 24 to 48 hours of life and lasts for 4 to 5 days. A Wright stain of the contents of a vesicle or pustule reveals numerous eosinophils.